The autoimmunity conundrum: clotting or inflammation
Identifieur interne : 001663 ( Main/Exploration ); précédent : 001662; suivant : 001664The autoimmunity conundrum: clotting or inflammation
Auteurs : Dennis Z. Y. Yee [Singapour] ; Gim Gee Teng [Singapour] ; Anita Y. N. Lim [Singapour] ; Adrian F. Low [Singapour] ; Sheila Vasoo [Singapour]Source :
- International Journal of Rheumatic Diseases [ 1756-1841 ] ; 2010-10.
English descriptors
- Teeft :
- Aiha, American heart association, Anticoagulant, Antiphospholipid, Antiphospholipid antibodies, Antiphospholipid syndrome, Autoimmune, Autoimmunity conundrum, Cardiac, Cardiac involvement, Cardiac manifestations, Cardiovascular, Cardiovascular disease, Catastrophic antiphospholipid syndrome, Clin, Duke criteria, Dysfunction, Ejection fraction, Endocarditis, Erythematosus, Higher prevalence, Hughes syndrome, Infective, Infective endocarditis, Inotropic support, International consensus statement, International journal, Intravenous, Intravenous drug abuse, Lupus, Lupus anticoagulant, Mitral, Myocardial infarction, Myocarditis, Possible infective endocarditis, Pregnancy losses, Primary antiphospholipid syndrome, Recurrent pregnancy losses, Renal, Rheumatic diseases, Rheumatological condition, Risk factors, Singapore, Syndrome, Systemic lupus erythematosus, Thrombocytopenia, Thrombosis, Transesophageal, Transesophageal echocardiography, Valvular, Valvular dysfunction, Ventricular.
Abstract
Antiphospholipid syndrome (APS) is an autoimmune condition with a myriad of clinical manifestations ranging from cardiovascular, neurologic, renal involvement to cutaneous manifestations and thrombocytopenia. We describe a young woman who presented with fever, cough and dyspnea. She had a history of recurrent pregnancy losses and her antiphospholipid antibodies and lupus serologies were positive. Echocardiography showed mobile mitral and aortic valve vegetations. She was treated as for infective endocarditis and diagnosed with primary APS with lupus‐like disease. Vigilance is required to establish if there is an underlying rheumatological condition in a patient who presents with presumptive infective endocarditis in the absence of risk factors. Treatment for systemic lupus erythematosus and primary APS are distinct.
Url:
DOI: 10.1111/j.1756-185X.2010.01534.x
Affiliations:
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We describe a young woman who presented with fever, cough and dyspnea. She had a history of recurrent pregnancy losses and her antiphospholipid antibodies and lupus serologies were positive. Echocardiography showed mobile mitral and aortic valve vegetations. She was treated as for infective endocarditis and diagnosed with primary APS with lupus‐like disease. Vigilance is required to establish if there is an underlying rheumatological condition in a patient who presents with presumptive infective endocarditis in the absence of risk factors. Treatment for systemic lupus erythematosus and primary APS are distinct.</div></front></TEI><affiliations><list><country><li>Singapour</li></country></list><tree><country name="Singapour"><noRegion><name sortKey="Yee, Dennis Z Y" sort="Yee, Dennis Z Y" uniqKey="Yee D" first="Dennis Z. Y." last="Yee">Dennis Z. Y. Yee</name></noRegion><name sortKey="Lim, Anita Y N" sort="Lim, Anita Y N" uniqKey="Lim A" first="Anita Y. N." last="Lim">Anita Y. N. Lim</name><name sortKey="Low, Adrian F" sort="Low, Adrian F" uniqKey="Low A" first="Adrian F." last="Low">Adrian F. Low</name><name sortKey="Teng, Gim Gee" sort="Teng, Gim Gee" uniqKey="Teng G" first="Gim Gee" last="Teng">Gim Gee Teng</name><name sortKey="Vasoo, Sheila" sort="Vasoo, Sheila" uniqKey="Vasoo S" first="Sheila" last="Vasoo">Sheila Vasoo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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